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Probing tumorigenic potentials of the genetic interactions reconstituted in murine fallopian tube organoids

ABSTRACT: Despite histological diversity in the subcutaneous nodules and tumors, the derived tumor-derived organoids stereotypically exhibited cystic featuresTo clarify molecular differences among the p53-null falopian tube-derived tumors driven by KrasG12D, Pik3caH1047R, and Apc580D, the transcriptome across tumor-derived organoidss, originating organoids before inoculation, p53-null organoids without driver mutations, and organoids without recombination as a reference were compared.

ORGANISM(S): Mus musculus

PROVIDER: GSE175511 | GEO | 2021/06/30

REPOSITORIES: GEO

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