Expression data of extracellular vesicles from bone metastatic breast cancer cell line

ABSTRACT: Bone metastasis is an incurable complication of breast cancer. In advanced stages, patients with estrogen-positive tumors experience significantly higher incidence of bone metastasis compared to estrogen-negative patients. To investigate how estrogen-positive breast cancer cells communicate with bone microenvironmental cells, extracellular vesicles from bone metastatic MCF7BoM2 were purified and analyzed. We used GeneChip miRNA 4.1 Array to detail the miRNA expression in the extracellular vesicles from the bone metastatic MCF7BoM2 and its parental cell line MCF7, and identified the dysregulated miRNAs.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE176105 | GEO | 2021/06/04

REPOSITORIES: GEO