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Protein Arginine Methyltransferase 1 is Essential for the Meiosis of Male Germ Cells

ABSTRACT: Methods: Prmt1 floxed mice were crossed with Rip2-Cre and Pdx1-CreERT2 mice to generate Prmt1 KO and Prmt1 iKO mice. R26-eYFP mice were crossed for lineage tracing experiments and cell sorting. All mice were backcrossed and maintained on a C57BL/6J background. Cre recombination for CreERT2 was induced by total 5 times intraperitoneal injections (75 mg/kg) of corn oil dissolved tamoxifen (T5648, Sigma-Aldrich) over 2 weeks.

ORGANISM(S): Mus musculus

PROVIDER: GSE176443 | GEO | 2021/08/11

REPOSITORIES: GEO

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