Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors
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ABSTRACT: In this study, our results demonstrated preclinical activity of combined DNMT and HDAC inhibition against chondrosarcomas and suggest that targeted epigenetic therapies could effectively augment the immune-reactivity of chondrosarcomas and may sensitize these immune-cold tumors to immune checkpoint blockade.
ORGANISM(S): Homo sapiens
PROVIDER: GSE178176 | GEO | 2021/12/08
REPOSITORIES: GEO
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