Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MiRNA profiling in URSA patients and control subjects

ABSTRACT: A total of 39 miRNAs were either up- or down- regulated by at least 1.5-fold and P value< 0.05 in the RSA, including 20 up-regulated miRNAs and 19 down-regulated miRNAs

ORGANISM(S): Homo sapiens

PROVIDER: GSE178619 | GEO | 2021/08/18

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Gene expression profiling of MRC-5 cells treated with 100 ug/mL regular-length pristine SWCNTs for 72 h

Project description:A total of 30 genes were up-regulated and 19 genes were down-regulated > 1.5-fold following 100 ug/mL regular-length pristine SWCNTs treatment

2016-11-23 | GSE89375 | GEO

Investigation of circular RNA expression profiles in ultrasound-guided radiofrequency ablation-treated transplanted tumor models of human liver cancer

Project description:Following RFA treatment, 76 DE-circRNAs were detected (|fold changes |>1.5, P-value <0.05), among which 21 were up-regulated and 55 were down-regulated.

2024-03-23 | GSE229348 | GEO

Phase separation of YAP-MAML2 differentially regulates the transcriptome

Project description:SPARK-OFF tag does not perturb the core transcriptional function of YAP-MAML2.~2260 DEGs with ≥ 1.5-fold change in transcript level, including ~1270 up-regulated genes and ~990 down-regulated genes can be identified from YAP-MAML2 overexpression HEK293T cells.We identified 88 DEGs (p-value < 0.01, |Log2FC| ≥ 0.58, FDR < 0.1) that are regulated by YAP-MAML2 phase separation with ≥ 1.5-fold change in transcript levels, including 44 up-regulated genes and 44 down-regulated genes

2024-01-23 | GSE253678 | GEO

Expression profiling of lncRNAs, miRNAs and mRNAs and their differential expression in leiomyoma using next generation RNA sequencing

Project description:Total RNA was isolated from leiomyoma and paired myometrium (N=8) and samples from three pairs were subjected to RNA sequencing. After analysis, 5941 lncRNAs (2813 up- and 3128 down-regulated at ≥1.5 fold), 148 miRNAs (56 up- and 96 down-regulated at ≥1.5 fold) and 3855 mRNAs (2030 up- and 1855 down-regulated at ≥1.5 fold) were differentially expressed in leiomyomas. Using QRT-PCR we further confirmed the expression of HULC, lnc-MEG3, LINC00890, TSIX, LINC00473, lnc-KLF9-1 and lnc-POTEM-3 (lncRNA-ATB) in leiomyoma and matched myometrium (N=8). Our results presented here provide a comprehensive expression profile of lncRNAs in leiomyomas with concurrent integrated expression of miRNAs and mRNAs in leiomyomas.

2017-06-22 | GSE100338 | GEO

miRNA expression of livers of liver-specific Hnf4a-null (Hnf4aΔH) mice

Project description:Of 610 miRNAs, expression of 24 and 19 miRNAs was down-regulated or up-regulated more than 2-fold in Hnf4aΔH mice as compared to control (Hnf4af/f) mice

2016-08-01 | GSE70516 | GEO

Expression data from Arabidopsis wild type and cdm1 young floral buds

Project description:We used microarray analysis to examine transcriptomic changes in cdm1 mutant, identifying genes potentially regulated by CDM1 by comparing gene expression between cdm1 and wild type young floral buds. Among 375 genes that showed differential expression (P-value <0.05) with >1.5-fold changes between wild type and cdm1, 185 genes were down-regulated by 1.5 to 7.10-folds, whereas 190 genes were up-regulated by 1.5 to 5.82-folds.

2014-03-11 | GSE55799 | GEO

The proteins of PK-15 cells infected with porcine parvovirus were identified and quantitatively analyzed by TMT labeling at 6 h and 36 h after infection, and the results were analyzed by gene ontology, KEGG and PPI bioinformatics.

Project description:In this project, TMT labeling quantitative proteomics technology was used to carry out the research, and a total of 4769 proteins were identified. The differentially expressed proteins were screened according to the criteria that the expression multiple changed more than 1.5 times (up-regulated more than 1.5 times or down-regulated less than 0.67 times) and P value < 0.05. The differentially expressed proteins were screened according to the criteria that the expression multiple changed more than 1.5 times (up-regulated more than 1.5 times or down-regulated less than 0.67). Among them, taking 6h VS 36h as an example, 120 differentially expressed proteins were up-regulated and 67 down-regulated. Through GO enrichment and KEGG pathway analysis, it was found that these differentially expressed proteins were mainly involved in important biological processes such as regulation of localization, cellular homeostasis, regulation of ion transmembrane transport, cytoskeleton organization and negative regulation of lymphocyte mediated immunity, and mainly involved in the regulation of important KEGG metabolic pathways such as Legionellosis, Steroid biosynthesis, Pentose and glucuronate interconversions, Adherens junction and Endocytosis.

2024-04-25 | PXD050764 | Pride

microRNA data involved in Japanese flounder (Paralichthys olivaceus) albinism

Project description:In this study, a high-throughput sequencing strategy was employed to identify the miRNAs involved in P. olivaceus albinism. High-throughput miRNA sequencing identified a total of 475 miRNAs, including 64 novel miRNAs. Furthermore, 33 differentially expressed miRNAs containing 13 up-regulated and 20 down-regulated miRNAs were identified in albino versus normally pigmented individuals (fold change ≥1.5 or ≤0.67 and p≤0.05).

2017-07-13 | GSE99342 | GEO

RNA-seq helps to analyze the regulation mechanism of maize roots under nutrient-deficiency conditions

Project description:To increase crop yield without polluting the environment, improving crop nutrient efficiency is of great importance. The RSA of plants is centrally involved in nutrient use efficiency. Therefore, to uncover the molecular mechanisms that regulate RSA of maize under nutrient-deficiency conditions and to improve maize nutrient use efficiency based on this knowledge, we investigated the morphological changes and ribonucleic acid sequencing (RNA-seq) profiles of maize roots during growth under normal and N-, P-, and K-deficiency conditions. We analyzed the data in different aspects and verified the reliability of the RNA-seq data by real-time quantitative polymerase chain reaction (RT-qPCR). These results will provide theoretical support for improving plant nutrient use efficiency. The maize (Z. mays) inbred line DengHai 605 was used in this study. Provided for four treatment conditions: normal N, P, and K level (CK); potassium deficiency (K-DEF); nitrogen deficiency (N-DEF); and phosphorus deficiency (P-DEF). The experiments were carried out by combining sand culture with water culture. The standard for evaluating differential gene expression is fold change (FC) > 2 or FC < -2 and p value < 0.05.The numbers of DEGs under N-, P-, and K-deficiency conditions were 3494 (1801 up-regulated and 1693 down-regulated), 3424 (1761 up-regulated and 1663 down-regulated), and 1830 (827 up-regulated and 1003 down-regulated), respectively. A total of 1483, 1470, and 519 genes were specifically expressed under the N-, P-, and K-deficiency conditions, respectively.

2022-01-01 | GSE125417 | GEO

miRNA sequencing of extracellular vesicles derived from podocytes under high glucose stimulation.

Project description:Extracellular vesicles were isolated from the cell culture supernatants of podocytes under high glucose(HG), normal glucose(NG) and iso-osmolality stimulation (three replicates/group). miRNA sequencing was performed to identify differentially expressed miRNAs in podocyte-derived extracellular vesicles. After sequencing, A total of 1915 miRNAs were annotated from all samples . A comparison of the HG and NG groups showed that 11 miRNAs were differentially expressed (4 for up-regulated and 7 for down-regulated,|log2(fold change)| > 1, p-value < 0.05), while a comparison of the HG and iso-osmolality groups showed that 18 miRNAs were differentially expressed (1 for up-regulated and 17 for down-regulated, |log2(fold change)| > 1, p-value < 0.05). This study provides the results of miRNA alteration in podocytes extracellular vesicles under HG stimulation.

2020-10-20 | GSE154284 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data