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Transcriptomes of miR-290-295 KO mESCs treated with siPOOLs for three different transcription factors and a negative control

ABSTRACT: In order to identify direct microRNA targets in mouse embryonic stem cells (mESCs), we generated miR-290-295 KO mutant cell lines, assessed their transcriptomes. We identified novel transcription factors (TF) as potential direct and functional targets of miR-290-295. To assess the role of these TFs, we rescued their expression in the miR-290-295 KO cell line using siPOOLs and profiled their transcriptomes.

ORGANISM(S): Mus musculus

PROVIDER: GSE179451 | GEO | 2022/07/15

REPOSITORIES: GEO

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Transcriptomes of miR-290-295 KO mESCs treated with siPOOLs against the transcription factor Tfap4

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