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The critical and diverse roles of CD4-CD8- double negative T cells in non-alcoholic fatty liver disease

ABSTRACT: Methods: RNA transcription profiling of intrahepatic CD4-CD8- double negative T cells were compared between C57BL/6 mice fed with control diet and methionine-choline deficient diet (MCD) for 5 weeks. Results: RNA sequencing data showed that intrahepatic DNT in NAFLD mice exhibited markedly decreased Prf1, Gzmb but increased Il17a expression.

ORGANISM(S): Mus musculus

PROVIDER: GSE180576 | GEO | 2021/07/22

REPOSITORIES: GEO

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