Transcriptomics

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Transcriptomic analysis of human laryngeal carcinoma cell line LIU-LSC-1 with depletion of Raptor


ABSTRACT: Recent studies have shown that mTOR signalling have a promotive effect on cancer. In our clinical work, we found that mTOR signalling is commonly activated in laryngeal cancer tissues and influence the metabolism of cancer cells. To investigate how mTORC1 exerts these functions and its downstream regulatory genes, we knocked down Raptor in the laryngeal cancer cell line LIU-LSC-1 and sequenced the transcriptome of wild-type and Raptor knockdown cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE180702 | GEO | 2022/11/03

REPOSITORIES: GEO

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