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16S V3-V4 -based microbial profiling of duodenal mucosa samples obtained by esophagogastroduodenoscopy from patients affected by potential celiac disease and celiac disease


ABSTRACT: Potential celiac diseasase (PCD) is characterized by a positive celiac disease (CD) serology and a normal small intestinal mucosa. This particular condition is usually considered a clinical challenge because, although its diagnostic criteria are clear, many questions are still unsettled. Therefore, given that PCD is a valuable biological model of the pathway leading to small intestinal mucosal damage in genetically predisposed individuals, the aim of our study is to evaluate whether immunological, microbial and lipid signatures could better characterize the PCD from the CD condition.

ORGANISM(S): Homo sapiens

PROVIDER: GSE181070 | GEO | 2022/10/19

REPOSITORIES: GEO

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