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Genome-wide localization profile (ChIP-seq) and differential expression profile upon RNAi treatment (RNA-seq) of L(3)mbt and its interactor in ovarian somatic cells[OSCs] in Drosophila

ABSTRACT: L(3)mbt regulate the transcription of germ-specific genes in somatic cells but the detailed mechanism remains unclear. We performed ChIP-seq of L(3)mbt and a newly identified interactor in OSCs to elucidate the genome-wide localization. Then we performed RNA-seq of OSCs before and after RNAi treatment of L(3)mbt and its interactors and performed differential expression analysis.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE181802 | GEO | 2022/08/15

REPOSITORIES: GEO

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Genome-wide localization profile (ChIP-seq) and differential expression profile upon RNAi treatment (RNA-seq) of L(3)mbt and its interactors in ovarian somatic cells[OSCs] in Drosophila

Project description:L(3)mbt regulate the transcription of germ-specific genes in somatic cells but the detailed mechanism remains unclear. We performed ChIP-seq of L(3)mbt and a newly identified interactor in OSCs to elucidate the genome-wide localization. Then we performed RNA-seq of OSCs before and after RNAi treatment of L(3)mbt and its interactors and performed differential expression analysis.

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Genome-wide localization profile (ChIP-seq) and differential expression profile upon RNAi treatment (RNA-seq) of L(3)mbt and its interactors in ovarian somatic cells[OSCs] in Drosophila

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