Genomics

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ChIP-seq on COMPASS-degron cells


ABSTRACT: Here, we showed that acute lost H3K4me3 induces rapid reduction in global transcription with progressively increase in magnitude over the time-course cooccurrence with lost all H3K4 methylations. To further determine the effects of COMPASS subunits degradation on H3K4 methylations occupancies genome-wide, we performed time-course spike-in chromatin immunoprecipitation and sequencing (ChIP-seq, also known as ChIP-Rx) analysis in both degron systems.

ORGANISM(S): Mus musculus

PROVIDER: GSE181892 | GEO | 2023/01/20

REPOSITORIES: GEO

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