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RNAseq analysis comparing siRNA knocked down FOXF2 in and MKX in human normotrophic scar dermal fibroblasts

ABSTRACT: 3mm punch biopsies were taken from a healed normotrophic scar in burn patients with a scar at least 1 year old and fibroblasts were cultured from explants. Previous transcriptomic and epigenomic work found MKX and FOXF2 genes were overexpressed and these were knocked down using siRNA. RNA was then extracted and analysed using RNAseq to determine genes and pathways affected by this knockdown

ORGANISM(S): Homo sapiens

PROVIDER: GSE182515 | GEO | 2021/08/27

REPOSITORIES: GEO

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A methylation analysis of human normotrophic scar dermal fibroblasts

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