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Transcriptomics in olfactory cells transfected with SARS-CoV-2 structural proteins

ABSTRACT: One of the most common symptoms in COVID-19 is a sudden loss of smell. SARS-CoV-2 has been detected in the olfactory bulb (OB) from animal models and sporadically in COVID-19 patients. To decipher the specific role of SARS-CoV-2 proteome at olfactory level, we deeply characterized the molecular imbalance induced by the expression of GFP-tagged SARS-CoV-2 structural proteins (M, N, E, S) on mouse OB cells by RNA-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE182849 | GEO | 2022/09/28

REPOSITORIES: GEO

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