Transcriptomics

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A multi-tissue study of immune gene expression profiling highlights the key role of the nasal epithelium in COVID-19 severity


ABSTRACT: COVID-19 symptoms range from mild to severe illness; the cause for this differential response to infection remains unknown. Unraveling the immune mechanisms acting at different levels of the colonization process might be key to understand these differences. We carried out a multi-tissue (nasal, buccal and blood) gene expression analysis of immune-related genes from patients affected by different COVID-19 severities, and healthy controls.

ORGANISM(S): Homo sapiens

PROVIDER: GSE183071 | GEO | 2021/12/31

REPOSITORIES: GEO

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