Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Eclipse, TSQ Quantiva, Q Exactive GC Orbitrap, Q Exactive HF
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: Ariel Jaitovich Joshua Coon
PROVIDER: MSV000085703 | MassIVE | Wed Jul 08 19:27:00 BST 2020
REPOSITORIES: MassIVE
Overmyer Katherine A KA Shishkova Evgenia E Miller Ian J IJ Balnis Joseph J Bernstein Matthew N MN Peters-Clarke Trenton M TM Meyer Jesse G JG Quan Qiuwen Q Muehlbauer Laura K LK Trujillo Edna A EA He Yuchen Y Chopra Amit A Chieng Hau C HC Tiwari Anupama A Judson Marc A MA Paulson Brett B Brademan Dain R DR Zhu Yunyun Y Serrano Lia R LR Linke Vanessa V Drake Lisa A LA Adam Alejandro P AP Schwartz Bradford S BS Singer Harold A HA Swanson Scott S Mosher Deane F DF Stewart Ron R Coon Joshua J JJ Jaitovich Ariel A
Cell systems 20201008 1
We performed RNA-seq and high-resolution mass spectrometry on 128 blood samples from COVID-19-positive and COVID-19-negative patients with diverse disease severities and outcomes. Quantified transcripts, proteins, metabolites, and lipids were associated with clinical outcomes in a curated relational database, uniquely enabling systems analysis and cross-ome correlations to molecules and patient prognoses. We mapped 219 molecular features with high significance to COVID-19 status and severity, ma ...[more]