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DSLAM

ABSTRACT: These datasets use diploid-based synthetic lethality analysis on microarrays (dSLAM) as a new technology for identifying genetic interactions of various types. These interactions include synthetic lethality (CIN8, BIM1, SGS1), synthetic haploinsufficiency (TUB1), dosage suppression (LCD1), suppression of a lethal mutation (SML1), suppression of an overexpressed conditionally lethal allele (CDC102), and gene-chemical interactions (Benomyl). Keywords = dSLAM yeast heterozygotes barcode tag synthetic lethality suppression Keywords: other

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE1838 | GEO | 2004/11/05

SECONDARY ACCESSION(S): PRJNA90565

REPOSITORIES: GEO

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SML1 synthetic lethality

Project description:Assessment of synthetic lethality between an sml1 null mutation and Yeast Deletion mutations Keywords = SML1 Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample

2004-11-05 | GSE1765 | GEO

SGS1 synthetic lethality

Project description:Assessment of synthetic lethality between an sgs1 null mutation and Yeast Deletion mutations Keywords = SGS1 Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample

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Benomyl dose-response

Project description:Synthetic lethality of Yeast Deletion strain mutations in haploid cells with various concentrations of Benomyl Keywords = Benomyl Keywords = yeast Keywords = deletion Keywords = tag Keywords = barcode Keywords: dose response

2004-11-05 | GSE1752 | GEO

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Synthetic Lethality (SLAM) Project Data

Project description:Synthetic lethality is a type of genetic interaction in which two non-lethal mutations acting together result in a loss of viability. Such interactions are important for the insights they may offer into how gene functions are organized into distinct cellular processes. The datasets in this Series represent an effort to identify synthetic lethal genetic interactions in the yeast Saccharomyces cerevisiae on a genome-wide scale. Please see the Pubmed IDs in the individual Sample annotations.

2013-02-28 | E-GEOD-14217 | biostudies-arrayexpress

BIM1 synthetic lethality

Project description:Assessment of synthetic lethality between a bim1 null mutation and Yeast Deletion mutations Keywords = BIM1 Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample

2004-11-05 | GSE1756 | GEO

CIN8 Synthetic Lethality

Project description:Assessment of synthetic lethality between a cin8 deletion mutation and Yeast Deletion mutations. Keywords = CIN8 Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample

2004-11-05 | GSE1754 | GEO

LCD1-overexpression synthetic lethality

Project description:Assessment of synthetic lethality between an overexpressed LCD1 gene and Yeast Deletion mutations Keywords = LCD1 Keywords = overexpression Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample

2004-11-05 | GSE1759 | GEO

Pool controls

Project description:Determination of how two critical procedural steps in the dSLAM protocol ('diploid synthetic lethality assessed by microarray') affect results Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: ordered

2004-11-05 | GSE1753 | GEO

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