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CIN8 Synthetic Lethality

ABSTRACT: Assessment of synthetic lethality between a cin8 deletion mutation and Yeast Deletion mutations. Keywords = CIN8 Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE1754 | GEO | 2004/11/05

SECONDARY ACCESSION(S): PRJNA90625

REPOSITORIES: GEO

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SML1 synthetic lethality

Project description:Assessment of synthetic lethality between an sml1 null mutation and Yeast Deletion mutations Keywords = SML1 Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample

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SGS1 synthetic lethality

Project description:Assessment of synthetic lethality between an sgs1 null mutation and Yeast Deletion mutations Keywords = SGS1 Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample

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BIM1 synthetic lethality

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LCD1-overexpression synthetic lethality

Project description:Assessment of synthetic lethality between an overexpressed LCD1 gene and Yeast Deletion mutations Keywords = LCD1 Keywords = overexpression Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample

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Project description:Assessment of synthetic lethality between a temperature-sensitive allele of CDC102 and Yeast Deletion mutations Keywords: repeat sample

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Project description:Assessment of growth impairment resulting from a heterozygous tub1 null mutation as compared to that from a heterozygous ura3 null mutation Keywords = TUB1 Keywords = URA3 Keywords = yeast Keywords = deletion Keywords = synthetic haploinsufficiency Keywords = tag Keywords = barcode Keywords: repeat sample

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Pool controls

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dSLAM

Project description:These datasets use diploid-based synthetic lethality analysis on microarrays (dSLAM) as a new technology for identifying genetic interactions of various types. These interactions include synthetic lethality (CIN8, BIM1, SGS1), synthetic haploinsufficiency (TUB1), dosage suppression (LCD1), suppression of a lethal mutation (SML1), suppression of an overexpressed conditionally lethal allele (CDC102), and gene-chemical interactions (Benomyl). Keywords = dSLAM yeast heterozygotes barcode tag synthetic lethality suppression Keywords: other

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Synthetic Lethality (SLAM) Project Data

Project description:Synthetic lethality is a type of genetic interaction in which two non-lethal mutations acting together result in a loss of viability. Such interactions are important for the insights they may offer into how gene functions are organized into distinct cellular processes. The datasets in this Series represent an effort to identify synthetic lethal genetic interactions in the yeast Saccharomyces cerevisiae on a genome-wide scale. Please see the Pubmed IDs in the individual Sample annotations.

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