Transcriptomics

Dataset Information

0

Hepatocytes cyclooxygenase-2 deficiency improves liver injury via inhibition of endoplasmic reticulum stress and epithelial-mesenchymal transition


ABSTRACT: The mechanism underlying the loss of normal liver tissues in liver cirrhosis, mainly hepatocytes, is not well-characterized. Endoplasmic reticulum (ER) stress-induced cell death has emerged as a potential mechanism for chronic liver diseases. We have previously demonstrated that cyclooxygenase-2 (COX-2) is closely related to the progress of liver cirrhosis. In this study, we aimed to verify whether hepatocytes COX-2 deficiency could protect liver injury via inducing ER stress in liver cirrhosis.

ORGANISM(S): Mus musculus

PROVIDER: GSE183888 | GEO | 2024/04/28

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2015-06-18 | E-GEOD-62263 | biostudies-arrayexpress
2011-02-17 | E-GEOD-27349 | biostudies-arrayexpress
2021-01-12 | GSE121557 | GEO
2015-05-12 | E-GEOD-68718 | biostudies-arrayexpress
2015-01-01 | GSE53975 | GEO
2011-02-17 | GSE27349 | GEO
2023-11-26 | GSE232677 | GEO
2012-01-20 | E-GEOD-29929 | biostudies-arrayexpress
2011-05-09 | E-GEOD-17711 | biostudies-arrayexpress
2018-10-31 | GSE99763 | GEO