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Expression of CCRL2 inhibits tumor growth by concentrating chemerin and inhibiting neoangiogenesis

ABSTRACT: CCRL2 is a non-signaling G protein-coupled receptor for chemerin, a leukocyte chemoattractant and an adipokine. Graft of B16 melanoma or Lewis lung carcinoma (LLC) cell lines in CCRL2 KO mice results in delayed growth of the tumors.

ORGANISM(S): Mus musculus

PROVIDER: GSE183914 | GEO | 2021/10/20

REPOSITORIES: GEO

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Chemerin inhibits cancer progression by impairing the maturation of neovessels

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Expression of CCRL2 inhibits tumor growth by concentrating chemerin and inhibiting neoangiogenesis

Project description:Expression of CCRL2 inhibits tumor growth by concentrating chemerin and inhibiting neoangiogenesis

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