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Chemerin inhibits cancer progression by impairing the maturation of neovessels

ABSTRACT: Chemerin is a leukocyte chemoattractant and an adipokine. Overexpression of chemerin by tumor cells or the host inhibits tumor progression in different mouse models, through a mechanism involving the chemerin receptor CMKLR1 and impairment of endothelial cell/pericyte interactions in neovessels.

ORGANISM(S): Mus musculus

PROVIDER: GSE98672 | GEO | 2019/05/05

REPOSITORIES: GEO

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Expression of CCRL2 inhibits tumor growth by concentrating chemerin and inhibiting neoangiogenesis

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