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Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. The study demonstrate that glycosyltransferase Extl1 plays critical roles in promoting CCR7-mediated DC migration by enhancing CCR7 expression and signaling via HSPG, thus contributing to immune defense against pathogens and prevention of autoimmune diseases.

ORGANISM(S): Mus musculus

PROVIDER: GSE184978 | GEO | 2023/01/19

REPOSITORIES: GEO

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Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity [treated vs. untreated]

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