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Genome-scale CRISPR screen reveals inhibitory factors as regulatory module of HIV

ABSTRACT: To identify host factors that restrict HIV replication, we conducted a CRISPR activation screen in a susceptible T cell line using a high-complexity, genome-wide sgRNA library. Our results identified host factors that conferred protection from HIV infection.

ORGANISM(S): Homo sapiens

PROVIDER: GSE185343 | GEO | 2022/06/04

REPOSITORIES: GEO

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Genome-scale CRISPR screen reveals inhibitory factors as regulatory module of HIV

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