LRG1 is an adipokine that mediates obesity-induced hepatosteatosis and insulin resistance [liver_RNA-seq]
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ABSTRACT: Dysregulation in adipokine biosynthesis and function contributes to obesity-induced metabolic diseases. However, the identities and functions of many of the obesity-induced secretory molecules remain unknown. This study identified Leucine-rich alpha-2-glycoprotein 1 (LRG1) as an obesity-associated adipokine. The effects of LRG1 deficiency on liver tissue gene expression were tested in current assay.
ORGANISM(S): Mus musculus
PROVIDER: GSE185483 | GEO | 2022/03/04
REPOSITORIES: GEO
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