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Gastric adenocarcinoma of fundic gland type vs matched normal mucosa

ABSTRACT: Background: Gastric adenocarcinoma of fundic gland type (GA-FG) is rare, and the mechanisms of carcinogenesis and growth progression have not to be elucidated. Results: Transcriptional profiles of 3 fresh-frozen GA-FG and surrounding normal mucosa were compared. Key features of gene expression analysis suggested that TTF-1/NKX2-1 acts as an important transcription factor in GA-FG. This study will provide insight into the mechanism of development. All samples were obtained prior to resection of target lesions in order to minimize effects of cauterization.

ORGANISM(S): Homo sapiens

PROVIDER: GSE185878 | GEO | 2024/10/10

REPOSITORIES: GEO

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