Transcriptomics

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Reversible dietary effect on intestinal stem cells


ABSTRACT: We report the application of bulk RNAseq assay in examining the dietary effect on mouse intestinal stem cell (ISC) subpopulation. Lgr5EGFPcreERT2 mice were fed with new western diet 1 (NWD1) or the control AIN76A diet for 3 or 12 months, to investigate differential dietary effect. To examine the reversibility of dietary effect, after 3 months of NWD1 feeding, the mice were switched to AIN feeding, and examined at 6 or 12 months old.

ORGANISM(S): Mus musculus

PROVIDER: GSE186811 | GEO | 2023/04/12

REPOSITORIES: GEO

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