Transcriptomics

Dataset Information

0

Dietary induced dedifferentiation of Bmi1 cells and its impact on intestinal mucosal homeostasis


ABSTRACT: Bmi1tm1(cre/ERT2)Mrc/J (a.k.a. Bmi1creERT2 mice), B6.Cg-Gt(ROSA)26Sortm14(CAT-tdTomato)Hze/J (a.k.a. Rosa26tom mice) were crossed. The mice were fed with New Western diet 1 (NWD1) or Americal Instititue of Nutrition 76A (AIN76A or AIN) diet from weaning for 3 months. Tamoxinfen was injected to induce Bmi1 cell dedifferentiation, featuring the expression of tomato red fluoresence in the Bmi1 locus. Single intestinal epithelial cells were FACS isolated by the Epcam+, CD45- and Tomato (red fluorescence)+, and subject to scRNAseq assay.

ORGANISM(S): Mus musculus

PROVIDER: GSE188338 | GEO | 2023/04/12

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-04-12 | GSE228006 | GEO
2024-03-27 | GSE221818 | GEO
2023-04-12 | GSE186811 | GEO
2011-05-31 | E-GEOD-29538 | biostudies-arrayexpress
2011-03-05 | E-GEOD-27684 | biostudies-arrayexpress
2019-12-01 | GSE39830 | GEO
2014-10-02 | E-GEOD-61939 | biostudies-arrayexpress
2023-06-20 | GSE235023 | GEO
2008-10-21 | E-GEOD-12028 | biostudies-arrayexpress
2014-09-03 | GSE61005 | GEO