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Sub-populations of c-Myb in MCF-7 cells

ABSTRACT: We compared two independent c-Myb antibodies during cellular confluence and estrogen stimulation to determine endogenous c-Myb target genes. Interestingly, we discovered that c-Myb specificity was estrogen dependent and multiple antibodies recognize distinct sets of endogenous targets suggesting that epitope masking and domains within the c-Myb protein play a critical role in the activity of the c-Myb protein.

ORGANISM(S): Homo sapiens

PROVIDER: GSE18706 | GEO | 2010/05/01

SECONDARY ACCESSION(S): PRJNA121499

REPOSITORIES: GEO

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Transcriptome sequencing of K562 cells stably expressing SUMO negative MYB

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