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Uncharged tRNAGln as an indicator of intracellular amino acid level upregulates UBC expression to maintain its charging level V

ABSTRACT: We profiled the cellular tRNA charging landscape using next-generation sequencing and identified a subset of tRNA that sense nutrients. The charging levels of tRNAGln were exclusively and significantly decreased in response to amino acid starvation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE188860 | GEO | 2022/11/30

REPOSITORIES: GEO

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