Uncharged tRNAGln as an indicator of intracellular amino acid level upregulates UBC expression to maintain its charging level VI
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ABSTRACT: We profiled the cellular tRNA charging landscape using next-generation sequencing and identified a subset of tRNA that sense nutrients. The charging levels of tRNAGln were exclusively and significantly decreased in response to amino acid starvation.
ORGANISM(S): Homo sapiens
PROVIDER: GSE188861 | GEO | 2022/11/30
REPOSITORIES: GEO
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