Transcriptomics

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Expression data from MDSC treated with STAT3 inhibitor Napabucasin


ABSTRACT: MDSC (myeloid-derived suppressor cells) were generated in vitro using IL-6 and GM-CSF. To identify the role of STAT3 in MDSC, we treated the generated cells for 24 hours with DMSO (control) or 1 µM STAT3 inhibitor Napabucasin (also known as BBI608) and compared their expression profile by microarray. We found genes and pathways that are up- or downregulated upon STAT3 inhibition in MDSC.

ORGANISM(S): Mus musculus

PROVIDER: GSE189147 | GEO | 2022/03/23

REPOSITORIES: GEO

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