Transcriptome analysis of nascent hematopoietic stem cells (HSCs) induced by the ectopic expression of Evi1
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ABSTRACT: To examine the role of Evi1 in HSC specification, we generated Tie2-Cre::ROSA-Evi1 mice, which can induce Evi1 in endothelial cells. We observed five-fold increase of HSCs In Tie2-Cre::ROSA-Evi1 embryo. To characterize the induced HSCs in Tie2-Cre::ROSA-Evi1 embryos, we analyzed the gene expression profile of HSCs.
ORGANISM(S): Mus musculus
PROVIDER: GSE190011 | GEO | 2022/06/22
REPOSITORIES: GEO
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