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Effect of hBD-2 treatment on gene expression in the colon of acute graft-versus-host disease (GVHD) mice

ABSTRACT: Wildtype (WT) BALB/c mice were treated with allogeneic hematopoietic cell transplantation (allo-HCT) in order to induce acute GVHD. C57BL/6 mice were used bone marrow (BM) and T cell donor mice. We studied the effect of oral hBD-2 treatment versus vehicle (PBS) control treatment on the gene expression in the colon, as main GVHD target organ.

ORGANISM(S): Mus musculus

PROVIDER: GSE190796 | GEO | 2022/12/23

REPOSITORIES: GEO

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