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Gene expression in hippocampus from ophn1tim1Bill mouse males and controls during 24h

ABSTRACT: Oligophrenin1 X-linked Intelectual disability (ID) gene is mutated in ID patients with cerebellar hypoplasia. It encodes OPHN1 protein which has been shown to interact with Rev-erb alpha, a negative regulator of the circadian clock in cells (https://doi.org/10.1038/nn.2911) In this study, we searched fo gene expression differences in hippocampi from adult mouse ophn1 KO and controls during 24 hours. Three replicates were collected evey 6 hours for both genotype. Data from controls were analyzed and reported in http://dx.doi.org/10.1016/j.neuroscience.2015.08.066.

ORGANISM(S): Mus musculus

PROVIDER: GSE190891 | GEO | 2021/12/24

REPOSITORIES: GEO

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