The Mediator Kinase Complex Cooperates with Swi/Snf to Regulate Lineage-Resolved Enhancers and Differentiation [RNA-Seq]
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ABSTRACT: To identify novel functions of Mediator kinases CDK8 and CDK19 in the intestinal epithelium, we generated novel genetic mouse model enabling the individual and compound deletion of CDK8 and CDK19. RNA-sequencing was performed on primary intestinal epithelial cells and murine small intestinal organoids at different time points after CDK8/19 deletion.
ORGANISM(S): Mus musculus
PROVIDER: GSE191123 | GEO | 2022/10/19
REPOSITORIES: GEO
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