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Integrated Analysis of lncRNA and mRNA Expression Profiles Indicates Age-related Changes in Meniscus

ABSTRACT: Little has been known about the role of long non-coding RNA (lncRNA) involves in meniscus degradation with aging.In order to investigate the molecular mechanisms of age-related meniscal degeneration and further explore potential biologic therapeutic targets, we performed microarray analysis of meniscus to determine lncRNAs and mRNAs expression profiles in young and aging adults. Then, we carried out bioinformatics analysis of differentially expressed molecules to identify key molecules and functional pathways in the aged meniscus tissues.

ORGANISM(S): Homo sapiens

PROVIDER: GSE191157 | GEO | 2022/04/06

REPOSITORIES: GEO

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