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Bulk RNA-seq on paws of collagen-induced arthritis (CIA) mouse model at different disease stages

ABSTRACT: The goal of this experiment is to profile longitudinal transcriptome changes during the development of murine arthritis in CIA mouse model. Male DBA1 mice (age between 10 to 12 weeks) were used in this study. CIA was induced by two immunizations with Type II collagen in Complete Freund’s adjuvant (CFA) at day 0, and with Type II collagen in Incomplete Freund’s adjuvant (IFA) at day 21. Bulk RNA-seq were done on right hind paws from control (non-immunized DBA1 mice) and CIA mice at different disease stages (up to 10 weeks after 1st immunization).

ORGANISM(S): Mus musculus

PROVIDER: GSE193335 | GEO | 2022/03/24

REPOSITORIES: GEO

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GENE EXPRESSION OF AN ANTI-INFLAMMATORY PENTAPEPTIDE ON CIA MURINE DEVELOPMENT

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Distinct Serum Proteome Profiles Associated with Collagen induced Arthritis, and Complete Freund’s Adjuvant-induced Inflammation in CD38-/- mice: the Discriminative Power of Protein Species or Proteoforms. Protein identification by Peptide Mass Fingerprinting (PMF)

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