Ontology highlight
ABSTRACT:
INSTRUMENT(S): 4800 Proteomics Analyzer
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Spleen
SUBMITTER: Antonio Rosal-Vela
LAB HEAD: Jaime Sancho Lopez
PROVIDER: PXD002644 | Pride | 2015-12-10
REPOSITORIES: Pride
Journal of proteomics 20151127
<h4>Unlabelled</h4>Collagen type II-induced arthritis (CIA) is an inflammatory and autoimmune disease. Spleen protein extracts were subjected to 2D-DiGE and MS-MALDI-TOF/TOF analysis to identify protein species that differ in abundance in CD38-KO versus B6 WT mice either with arthritis or with inflammation. Using multivariate analyses, in Col-II-immunized mice, 23 distinct spleen protein species were able to discriminate between WT and CD38-KO mice. Among them, several citrullinated proteins and ...[more]