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Targeting Histone Demethylase LSD1 for Treatment of Deficits in Autism Mouse Models [RNA-seq]

ABSTRACT: We performed RNAseq experiments to examine genome-wide transcriptional changes in PFC of Shank3 +/∆C mice with or without GSK-LSD1 treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE193380 | GEO | 2022/01/13

REPOSITORIES: GEO

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Targeting Histone Demethylase LSD1 for Treatment of Deficits in Autism Mouse Models [ChIP-seq]

Project description:We performed chromatin immunoprecipitation sequencing (ChIPseq) to profile genome-wide occupancy of H3K4me2 in PFC from WT mice and Shank3 +/∆C Tau mice.

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Targeting Histone Demethylase LSD1 for Treatment of Deficits in Autism Mouse Models

Project description:This SuperSeries is composed of the SubSeries listed below.

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Targeting Histone Demethylase LSD1 for Treatment of Deficits in Autism Mouse Models

Project description:Targeting Histone Demethylase LSD1 for Treatment of Deficits in Autism Mouse Models

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