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Photoconversion of MC38

ABSTRACT: MC38 tumors were photoconverted in Kade mice to assess the effect of photo conversion on the transcriptome

ORGANISM(S): Mus musculus

PROVIDER: GSE193654 | GEO | 2022/04/08

REPOSITORIES: GEO

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Effects of Id1 depletion in TAMs on the genes expression of MC38 cells.

Project description:We report the application of high-throughput mRNA sequencing to explore the effect of Id1 depletion in TAMs on gene expression of MC38 cells. Different groups of TAMs were isolated from the subcutaneous tumors in Id1f/f or myeloid cell lineage speciﬁc Id1 deficient mice (Id1-Lyz-KO) . MC38 cells were then mixed with two groups of TAMs and be implanted in C57BL/6J mice. CD45- cells were then isolated from the subcutaneous tumors described above to do the transcriptome sequencing.

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