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Transcriptome analysis of human 293T cells transfected with Ehhadh WT and different mutants (K329R, K335R, K344R, K572R)

ABSTRACT: We previously identified four lysine crotonylation (Kcr) sites at EHHADH (K329, K335, K344, K572). Ehhadh mutants in which lysine Kcr sites were simultaneously mutated to arginine by site-specific mutagenesis to mimic a decrotonylated status.To investigate the possible site-specific regulatory role of Ehhadh Kcr on biological processes, we performed transcriptome analysis on 293T cells that transfected with Ehhadh WT or mutants (K to R) recombinant Myc-tagged plasmids.

ORGANISM(S): Homo sapiens

PROVIDER: GSE194202 | GEO | 2022/01/25

REPOSITORIES: GEO

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Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

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