Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Light-activated molecular machines are new mode-of-action, fast-acting broad-spectrum antibacterials that target the membrane

ABSTRACT: Light-activated molecular machines (MNM) are synthetic molecular structures that, following light activation, undergo successive unidirectional rotation that results in a drilling-like rapid motion that can thrust the motor through biological membranes.Visible light (405 nm) activated MM were investigated for their antibacterial potential and their mechanism of action was investigated by RNAseq.

ORGANISM(S): Escherichia coli

PROVIDER: GSE194286 | GEO | 2022/01/27

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Light-activated molecular machines are new mode-of-action, fast-acting broad-spectrum antibacterials that target the membrane

Project description:Light-activated molecular machines are new mode-of-action, fast-acting broad-spectrum antibacterials that target the membrane

| PRJNA800066 | ENA

Differential Gene Expression Profile in the Rat Caudal Vestibular Nucleus is Associated with Individual Differences in Motion Sickness Susceptibility

Project description:Motion sickness susceptible (MSS) and insusceptible (inMSS) rats were identified by quantifying rotation-induced MS symptoms: defecation and spontaneous locomotion activity. Microarray analysis was used to screen differentially expressed genes in the caudal vestibular nucleus (CVN) after rotation.

2015-01-08 | E-MTAB-3213 | biostudies-arrayexpress

Expression profile of rat kidney of fetuses with 19 days of gestation under chronic rotation of the photoperiod.

Project description:Previously, we reported that of pregnant dams rats exposure to continues light and rotation of photoperiod have detrimental effects on the mother, fetus and adult offspring, with changes in the expression profile of fetal heart and liver. We investigated whether the chronic rotation of the photoperiod (CPS) during gestation can modify the fetal kidney expression profile at gestational day 19 by Affymetrix microarray analysis.

2019-06-06 | GSE130744 | GEO

RNAseq analysis of Campylobacter jejuni exposed to 405nm light

Project description:Campylobacter jejuni is susceptible to killing through exposure to blue light (405 nm) due to its poor ability to detoxify reactive oxygen species. This analysis aimed to elucidate the transcriptomic response of Campylobacter jejuni exposed to 405 nm light through illumina sequencing. C. jejuni was grown and exposed to 405nm light. Samples were taken at 15 min (7 J cm-1) and 30 min (14 J cm-1) after exposure. The data generated were compared to the transcriptome pre-exposure to determine the changes associated with blue light exposure

2022-07-21 | E-MTAB-11501 | biostudies-arrayexpress

Fast mode decomposition in few-mode fibers.

Project description:Retrieval of the optical phase information from measurement of intensity is of a high interest because this would facilitate simple and cost-efficient techniques and devices. In scientific and industrial applications that exploit multi-mode fibers, a prior knowledge of spatial mode structure of the fiber, in principle, makes it possible to recover phases using measured intensity distribution. However, current mode decomposition algorithms based on the analysis of the intensity distribution at the output of a few-mode fiber, such as optimization methods or neural networks, still have high computational costs and high latency that is a serious impediment for applications, such as telecommunications. Speed of signal processing is one of the key challenges in this approach. We present a high-performance mode decomposition algorithm with a processing time of tens of microseconds. The proposed mathematical algorithm that does not use any machine learning techniques, is several orders of magnitude faster than the state-of-the-art deep-learning-based methods. We anticipate that our results can stimulate further research on algorithms beyond popular machine learning methods and they can lead to the development of low-cost phase retrieval receivers for various applications of few-mode fibers ranging from imaging to telecommunications.

| S-EPMC7606473 | biostudies-literature

Alison Hughes Thesis - Chapter 5: Effect of 405 nm on Microalgae

Project description:Extracts from Dunaliella primolecta, Nannochloropsis oculata, Phaeodactylum tricornutum, and Porphyridium cruentum grown under 405 nm and white light in MiicroPharos photobioreactors

2021-09-08 | MSV000088069 | MassIVE

GNPS Alison Hughes Thesis - Chapter 5: Effect of 405 nm on Microalgae

| MSV000088069 | GNPS

Ultra-fast transcriptional responses in plants

Project description:Transcriptome of plants exposed to 0, 20 and 60 sec light stress was analyzed using Illumina HiSeq2000. We found that mRNA accumulation of more than 700 transcripts in plants occurs as early as 20-60 sec following light stress application

2016-12-06 | GSE60865 | GEO

A binary redox control mode in gene expression and metabolism of plants

Project description:To analyze the impact of photosynthetic redox signals, light sources with spectral qualities that preferentially excite either Photosystem I (PSI light) or Photosystem II (PSII light) were used. The light sources have been described in (Fey et al., 2005). Strong reduction and oxidation signals were induced by light shifts from PSI to PSII light (PSI-II) and the reverse light shift (PSII-I), respectivly. The acclimation responses were monitored at 0.5, 2, 8, and 48h after a light shift. Samples taken prior to changing the light quality (0h) served as control. Keywords: photosynthesis, redox regulation, light acclimation, retrograde signalling, long term response

2009-07-30 | GSE9235 | GEO

Blue‐shifting green fluorescent proteins using REPLACE

Project description:In the directed evolution experiments of EGFP or StayGold, the objective was to blue-shift the excitation light spectrum of GFP towards shorter wavelengths, resulting in an enhancement of fluorescence intensity upon 405 nm laser excitation. This facilitates the advancement of novel fluorescent proteins. These experiments represent a category of experiments that utilize REPLACE to achieve discontinuous directed evolution through FACS sorting (screening).

2024-09-30 | GSE271876 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data