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Gene expression in the hTSCs of si-NC and si-PR-SET7 KD hTSCs

ABSTRACT: To detect the gene profiles in si-NC and si-PR-SET7 KD hTSCs, hTSCs are collected and subjected to RNA-Seq. After aligned to mouse hg38 by HISAT2, RPKM value was calculated by Edger. Our results show that PR-SET7 as the key regulator for hTSCs. There are also some genes differentially expressed after PR-SET7 KD, some of the DEGs were further confirmed by qPCR, the DEGs were associated with viral mimic inflammatory activities, antiviral innate immune response, genomic instability, and programmed cell death, indicating the essential role of PR-SET7. This RNA-Seq data provides fundamental information for our further physiological study of PR-SET7.

ORGANISM(S): Homo sapiens

PROVIDER: GSE196223 | GEO | 2023/06/28

REPOSITORIES: GEO

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Gene expression in the hTSCs of si-NC and si-PR-SET7 KD hTSCs

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