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Donor T-cell DNMT3a regulates alloreactivity in murine models of hematopoietic stem cell transplantation [WGBS]

ABSTRACT: Donor T-cell methylation state has an effect on alloreactivity. We applied WGBS and the InformME analysis pipeline to investigate the role of DNA methylation in mice receiving transplantation from T-cell conditional DNMT3a KO donors.

ORGANISM(S): Mus musculus

PROVIDER: GSE196541 | GEO | 2022/06/13

REPOSITORIES: GEO

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