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Gene changes associated with deletion of Esrrg in Dopaminergic neurons in mice [H202SC21050050]

ABSTRACT: Purpose: The goal of this study is to understand what gene changes are associated with removal of Esrrg in dopaminerigc neurons from the mouse midbrain using BAC-TRAP and an AAV for Thcre Methods: Midbrain from mice expressing the L10a transgene used for BAC-TRAP method of RNA isolation both with and without deletion of Esrrg using AAV:THCre were aged 1 month post-injection and midbrains were then extracted and flash frozen on dry ice. RNA was isolated using the BAC-TRAP method and samples were sent for sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE198216 | GEO | 2022/08/22

REPOSITORIES: GEO

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Esrrg inhibition protects against PM2.5-induced asthma aggravation by reducing Pde3b

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