Genomics

Dataset Information

0

Coilin and Pol II ChIP-seq in HeLa cells after RPL14 and RPL24 depletion


ABSTRACT: To investigate location of Cajal bodies (CB) inside the cell nucleus after RPL depletion, we performed ChIP-seq with an anti-Coilin antibody after siRNA knockdown of RPL14 and RPL24. ChIP-seq revealed a loss of association of CBs wih snRNA genes and histone genes in histone cluster 1 and 2 upon RPL KD. We also performed Pol 2 ChIP-seq to look at transcription of these gene loci upon RPL knockdown and found decreased Pol II binding along genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE199275 | GEO | 2024/03/27

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2014-11-06 | E-GEOD-58449 | biostudies-arrayexpress
2014-11-06 | GSE58449 | GEO
2014-11-06 | GSE58448 | GEO
2014-11-06 | E-GEOD-58448 | biostudies-arrayexpress
2021-03-15 | GSE168888 | GEO
2023-07-27 | PXD027146 | Pride
2023-05-12 | PXD036370 | Pride
2022-06-30 | GSE182639 | GEO
2022-10-14 | PXD029502 | Pride
2024-05-14 | GSE246256 | GEO