Genomics

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The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract [ChIP-Seq]


ABSTRACT: We identify an unexpected functional role for E3 in fetal reproductive system and brain. We further identify a novel mechanism of estrogen action, through recruitment of epigenetic modifiers to estrogen receptors and their target genes, which doesn’t correlated with the traditional view of estrogen potency.”

ORGANISM(S): Homo sapiens

PROVIDER: GSE199293 | GEO | 2023/03/23

REPOSITORIES: GEO

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