PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation
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ABSTRACT: In this setup we have used RNA-seq, ChIP-seq, and ATAC-seq to identify how natural mutations in PPARg, which leads to lipodystrophy, cause changes in transcription, chromatin landscape, transcription factor binding and enhancer activity.
ORGANISM(S): Mus musculus
PROVIDER: GSE199426 | GEO | 2022/10/27
REPOSITORIES: GEO
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