Comparison of the effects of HIIT and exo-miRNAs upon obesity-associated metabolic dysfunction in HFD mice.
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ABSTRACT: We treated obese mice being fed a high-fat diet with exosomes transfected with a combination of inhibitors of obesity-associated miR-122 and miR-192 and a mimic of exercise-associated miR-133b. We used microarrays to detail the global changes of gene expression induced by the exosomal treatment in liver, adipose and muscle tissues in comparison with HIIT.
ORGANISM(S): Mus musculus
PROVIDER: GSE199465 | GEO | 2022/11/29
REPOSITORIES: GEO
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