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Transcriptional Characterization of Human Embryonic Stem Cell-Derived Endothelial Cells

ABSTRACT: Differentiation of human embryonic stem cells into endothelial cells (hESC-ECs) has the potential to provide an unlimited source of cells for novel transplantation therapies of ischemic diseases by supporting angiogenesis and vasculogenesis. In this study, we developed an extracellular matrix culture system for increasing endothelial differentiation and free from contaminating animal cells. We investigated the transcriptional changes that occur during endothelial differentiation of hESCs using whole genome microarray, and compared to human umbilical vein endothelial cells (HUVECs). (Note: Please see our publication, PMID 20046878, which includes analysis of array data from GSM348001-GSM348004 in conjunction with this series).

ORGANISM(S): Homo sapiens

PROVIDER: GSE20013 | GEO | 2010/01/28

SECONDARY ACCESSION(S): PRJNA124085

REPOSITORIES: GEO

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