Transcriptomics

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Determination of MHV virion genome poly(A) tail length and 3' end additions.


ABSTRACT: The mouse hepatitis virus (MHV) genomic RNA has a poly(A) tail required for replication. Here we investigated the presence of terminal poly(A) tail uridylation and guanylation in the virion RNA. After isolating the viral RNA followed by sequencing, we found a mean poly(A) tail of 66 nucleotides long with a peak of terminal uridylation on tails 55 to 66 nucleotides long.

ORGANISM(S): Murine hepatitis virus

PROVIDER: GSE200415 | GEO | 2023/03/23

REPOSITORIES: GEO

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